Srikar Yadhunandan
Writing

Engineering notes.

Architecture decisions, benchmarks, failure tests, open-source work, and what changed when implementation disagreed with the plan.

8 min · gpu / metal / cpp / bioinformatics / performance

MetalSW: When My GPU Code Lost to the CPU

I built exact Smith–Waterman protein search on Apple Silicon. The first serious benchmark lost to Parasail. This is what I measured, what I got wrong, and what eventually pushed the GPU to 13.5× the CPU SIMD baseline at 50,000 sequences.

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